منابع مشابه
Low-dose aspirin therapy to prevent preeclampsia.
OBJECTIVE Our aim was to test the hypothesis that acetylsalicylate (aspirin) treatment reduces the incidence or severity of pregnancy-associated hypertension. STUDY DESIGN Patients were nulliparous, healthy, and with a singleton gestation at between 20 and 22 weeks' gestation. A sample size of 600 patients was calculated on the basis of p < or = 0.05 and 90% power of observation. A 2-week pla...
متن کاملIs low-dose aspirin really harmful to the small bowel?
dose aspirin or no drugs for 14 days by a crossover method including a washout period for at least 4 weeks. After 2 weeks of treatment, significantly higher percentages of subjects in the aspirin group compared to the control group (80 vs. 20%) had small bowel pathology, however, there was no significant difference in the incidence of small bowel mucosal breaks. The main conclusion of this cros...
متن کاملPlatelet response to low-dose enteric-coated aspirin in patients with stable cardiovascular disease.
OBJECTIVES We investigated whether use of low-dose enteric-coated (EC) aspirin for secondary prevention of cardiovascular events has sufficient bioavailability to achieve complete platelet cyclooxygenase (COX) inhibition in all individuals. BACKGROUND Aspirin reduces cardiovascular morbidity and mortality in patients with pre-existing vascular disease; however, there is variability in the way...
متن کاملSex differences in platelet reactivity and response to low-dose aspirin therapy.
CONTEXT Recent randomized trials suggest that women may not accrue the same cardioprotective benefits as men do from low-dose aspirin therapy used in primary prevention. Failure of aspirin to suppress platelet aggregation in women is one hypothesized mechanism. OBJECTIVE To examine differential platelet reactivity to low-dose aspirin therapy by sex. DESIGN, SETTING, AND PARTICIPANTS A clini...
متن کاملProphylactic Low-Dose Aspirin Therapy
Background. The influence of prophylactic low-dose aspirin on the clinical characteristics of subsequent nonfatal myocardial infarction was examined in the Physicians' Health Study, a randomized, double-blind placebo-controlled trial of alternate-day aspirin (325 mg) among 22,071 US male physicians. Methods and Results. During 60.2 months of follow-up, 342 incident cases of nonfatal myocardial ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1968
ISSN: 0007-0912
DOI: 10.1093/bja/40.6.433